Hot flushes

The place for all those subjects that are of interest to women but might embarrass men.

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Hurghada Lady
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Post by Hurghada Lady » Fri Feb 20, 2009 9:36 pm

Fingers crossed it helps Patsy.



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Post by Karenh » Sat Feb 21, 2009 10:04 pm

Hi HL, I might try to get these tablets here~ just as I thought it was safe togo to bed and sleep and the moods were easing!!!! Or is it just withdrawal from Egypt and the sun? hmm i wonder! :lol:
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Post by Hurghada Lady » Sat Feb 21, 2009 11:53 pm

Well, I am hoping Patsy comes back in a couple of weeks posting that the tablets are working for her. If you try them Karen you can come back and report on them also ;)

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Post by P666ats » Mon Feb 23, 2009 6:54 pm

Well ladies the saga continues, went to the pharmacy for the pills and low and behold he said sorry cannot get them here... I asked if he could order some and he said the company that supplies them only do so every 6 to 12 mths and he doesnt know if they will be in Egypt any time soon. I asked him could he get me anything else maybe same thing but under a different name and guess what a big fat NO was his answer. Back to the drawing board for me, thanks ladies.
xxx

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Post by Hurghada Lady » Mon Feb 23, 2009 7:03 pm

Right.....I will go back in tomorrow night and he can look up when I see him, I can tell you. Will report back :x

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Post by Hurghada Lady » Wed Feb 25, 2009 12:34 pm

Hi P666ats,


What about this one? I met a friend of mine who owns a Pharmacy in Royal Palace Hotel (By Giftun Hotel). He advised this tablet, he said his mother had a hysterectomy last year and he put her on these tablets and they have worked wonders.....took about a month to work. I have told him you will phone him or pop in to see him. Might be better to phone him first to make sure he is there, I will send you a PM with his number. Fingers Crossed this one works out.

Livial

How does it work?

Livial tablets contain the active ingredient tibolone, which is a synthetic steroid medicine used for hormone replacement therapy (HRT). It mimics the activity of the female sex hormones oestrogen and progesterone and the androgen testosterone in the body.

Oestrogen is the main sex hormone in the female body. Certain parts of the body, such as the vagina, bones and breasts, rely on oestrogens to function normally. When the levels of oestrogen are low, these tissues can slowly degenerate, as is experienced during and following the menopause. In addition, low levels of oestrogen can cause distressing symptoms such as hot flushes, night sweats, mood swings or depressed mood, reduced sex drive and vaginal dryness. Oestrogen levels decrease naturally during the menopause, but also decrease following a hysterectomy (surgical menopause) and in women taking medicines called gonadorelin analogues, eg leuprorelin for endometriosis.

When taken by mouth, tibolone is broken down into three compounds that act in a similar way to the natural oestrogen, progesterone and testosterone found in the body. This helps restore the balance of hormones in the body and reduces the symptoms of menopause, whether natural or otherwise.

Tibolone is also sometimes used to prevent osteoporosis in postmenopausal women. The declining level of oestrogen at menopause can affect the bones, causing them to become thinner and more prone to breaking. Tibolone's oestrogenic effect can help prevent bone loss and fractures that may occur in women in the years after menopause. However, it is only used as a second-line option for women at high risk of fractures who cannot take other medicines that are licensed for preventing osteoporosis.

Women considered to be at high risk of developing fractures following the menopause include those who have had an early menopause, those with a family history of osteoporosis, those who have had recent prolonged corticosteroid therapy (eg prednisolone), those with a small thin frame, and smokers.

Women experiencing a natural menopause should not start treatment with this medicine until twelve months after their last natural menstrual bleed. This is because the medicine may cause irregular menstrual bleeding if it is started sooner than this.

Women who have had a surgical menopause or are taking gonadorelin analogues can start treatment immediately.

What is it used for?


Relieving the symptoms of oestrogen deficiency (eg hot flushes, decreased sex drive, depression) in women who have gone through the menopause.


Prevention of osteoporosis in women who have gone through the menopause and are at high risk of fractures, but cannot take other medicines used to prevent osteoporosis.


Warning!


Women taking any form of HRT should have regular medical and gynaecological check-ups. Your need for continued HRT should be reviewed with your doctor at least once a year.


It is important to be aware that all women using HRT have an increased risk of being diagnosed with breast cancer compared with women who don't use HRT. This risk needs to be weighed against the personal benefits to you of taking HRT. There is more detailed information about the risks and benefits associated with HRT in the factsheet about the menopause linked above. You should discuss these with your doctor before starting HRT. Women on HRT should have regular breast examinations and mammograms and should examine their own breasts regularly. Report any changes in your breasts to your doctor or nurse.


It is important to be aware that women using HRT have a slightly increased risk of stroke and of blood clots forming in the veins (eg deep vein thrombosis/pulmonary embolism) compared with women who don't use HRT. The risk is higher if you have existing risk factors (eg personal or family history, smoking, obesity, certain blood disorders - see cautions below) and needs to be weighed against the personal benefits to you of taking HRT. There is more detailed information about the risks and benefits associated with HRT in the factsheet about the menopause linked above. Discuss these with your doctor before starting treatment. It is not currently known if tibolone carries the same risk of blood clots as other forms of HRT. However it is associated with a slightly increased risk of stroke.


The risk of blood clots forming in the veins (thromboembolism) while taking HRT may be temporarily increased if you experience major trauma, have surgery, or are immobile for prolonged periods of time (this includes travelling for over five hours). For this reason, your doctor may recommend that you stop taking HRT for a period of time (usually four to six weeks) prior to any planned surgery, particularly abdominal surgery or orthopaedic surgery on the lower limbs, or if you are to be immobile for long periods. The risk of blood clots during long journeys may be reduced by appropriate exercise during the journey and possibly by wearing elastic hosiery. Discuss this with your doctor.


You may get some breakthrough bleeding or spotting in the first few months of taking this medicine. Missing a dose may increase the chance of this. If you are still experiencing any bleeding after six months of taking this medicine, or if breakthrough bleeding or spotting starts after this time, or after you have stopped taking this medicine, you should consult your doctor so that it can be investigated. This is because HRT, including tibolone, has been associated with a slightly increased risk of endometrial cancer. This risk needs to be weighed against the personal benefits to you of taking HRT and you should discuss this with your doctor before you start treatment.


Stop taking this medicine and inform your doctor immediately if you experience any of the following symptoms while taking this medicine: stabbing pains or swelling in one leg; pain on breathing or coughing; coughing up blood; breathlessness; sudden chest pain; sudden numbness affecting one side or part of the body; fainting; worsening of epilepsy; migraine or severe headaches; visual disturbances; severe abdominal complaints; increased blood pressure; itching of the whole body; yellowing of the skin or eyes (jaundice); or severe depression.


A woman is considered fertile for two years after her last menstrual period if she is under 50, or for one year if over 50. HRT does not provide contraception for women who fall within this group. If a potentially fertile women is taking HRT but also requires contraception, a non-hormonal method (eg condoms or contraceptive foam) should be used.


Use with caution in


Close family history of breast cancer (eg mother, sister or grandmother has had the disease)


History of benign breast lumps (fibrocystic breast disease)


History of fibroids in the womb


History of endometriosis


History of overgrowth of the lining of the womb (endometrial hyperplasia)


Personal or family history of blood clots in the veins (venous thromboembolism, eg deep vein thrombosis or pulmonary embolism)


Blood disorders that increase the risk of blood clots in the veins, eg antiphospholipid syndrome, factor V Leiden


Women taking medicines to prevent blood clots (anticoagulants), eg warfarin


Long-term inflammation of skin and some internal organs (systemic lupus erythematosus)


Personal or family history of recurrent miscarriage


Severe obesity


Varicose veins


Smokers


History of high blood pressure (hypertension)


Raised levels of fats called triglycerides in the blood (hypertriglyceridaemia)


History of liver disease, eg liver cancer


Decreased kidney function


Heart failure


History of diabetes


History of gallstones


History of migraines or severe headaches


History of epilepsy


History of asthma


History of an ear disorder that may cause hearing loss (otosclerosis)


History of irregular brown patches appearing on the skin, usually of the face, during pregnancy or previous use of hormone preparations such as contraceptive pills (chloasma). Women with a tendency to this condition should minimise their exposure to the sun or UV light while taking HRT.


Not to be used in


Pregnancy


Breastfeeding


Known, suspected or past history of breast cancer


Known or suspected cancer in which growth of the cancer is stimulated by oestrogen, eg cancer of the lining of the womb (endometrial cancer)


Untreated overgrowth of the lining of the womb (endometrial hyperplasia)


Vaginal bleeding of unknown cause


Women with a blood clot in a vein of the leg (deep vein thrombosis) or in the lungs (pulmonary embolism), or a past history of these conditions where the cause is unknown


History of angina


Women who have had a heart attack


Women who have had a stroke or mini-stroke (transient ischaemic attack or TIA)


Active liver disease


History of liver disease when liver function has not returned to normal


Hereditary blood disorders known as porphyrias


Rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption (Livial tablets contain lactose).


This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.


This medicine should not be used by women who are pregnant or breastfeeding. You should stop taking this medicine and consult your doctor immediately if you get pregnant during treatment.


A woman is considered fertile for two years after her last menstrual period if she is under 50, or for one year if over 50. HRT does not provide contraception for women who fall within this group. If you could get pregnant while taking this HRT, you should use a non-hormonal method of contraception (eg condoms or contraceptive foam). Seek medical advice from your doctor.


Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.


Vaginal bleeding or spotting


Vaginal discharge


Vaginal thrush


Vaginal itching


Breast pain


Disturbances of the gut such as diarrhoea, constipation, nausea, vomiting or abdominal pain


Rash or itching


Seborrhoeic dermatitis


Abnormal hair growth (hypertrichosis)


Dizziness


Headache/migraine


Weight gain


Visual disturbances such as blurred vision


Excessive fluid retention in the body tissues, resulting in swelling (oedema)


Pain in the muscles and joints


Depression


Alteration in results of liver function tests


Irregular brown patches on the skin, usually of the face (chloasma)


Blood clots in the blood vessels (eg, DVT, pulmonary embolism, heart attack, stroke - see warnings above)


The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while taking this one, to ensure that the combination is safe.

The following medicines may potentially reduce the blood levels and effect of this medicine, which could result in recurrence of symptoms or irregular bleeding:


antiepileptic medicines such as carbamazepine, phenytoin, phenobarbital and primidone


barbiturates such as amobarbital


rifamycin antibiotics such as rifabutin and rifampicin.


Some women with diabetes may need small adjustments in their dose of insulin or antidiabetic tablets while taking this medicine. You should monitor your blood sugar and seek advice from your doctor or pharmacist if your blood sugar control seems to be altered after starting this medicine.

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Post by P666ats » Sat Feb 28, 2009 10:07 am

Woo Hoo i think i have it cracked ladies, The pharmacist just up from Abu Ashra on the espalada made some calls for me yesterday about Klimadynon and he said he can get it for me. I have asked him to get me 3 boxes which have 30 tablets in each and cost 30le. I have to go tonight and pick them up (fingers crossed) and he said if i need more to go back to him. I can't take Livial as i am a diabetic and he said it would cause problems. Thanks for all your help and i will keep you informed how things go. Take care all. xxx

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Post by Hurghada Lady » Sat Feb 28, 2009 4:19 pm

Brilliant, which Pharmacy, is this the first one next to Macdonalds that said he couldn't get it after he told me he could?

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Post by P666ats » Sat Feb 28, 2009 4:26 pm

No hun it's the one by Abu Ashra, in between Abu's and KFC. He is really good but he was in Cairo for a few weeks having an operation but saw him yesterday and grabbed him. Will let you all know if he has got them as i have to go tonight. xx

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Post by Hurghada Lady » Sat Feb 28, 2009 4:35 pm

Good luck then x

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Post by Goddess » Sat Feb 28, 2009 5:09 pm

Keeping fingers crossed for you P. :)
Woo Hoo!!!!! I've got a signature!

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Post by P666ats » Sat Feb 28, 2009 9:27 pm

Well ladies true to his word he had the tablets and said if i need anymore it wont be a problem (bless him) i could have kissed him. Have to take one in the morning and one at night so fingers crossed they work. The pharmacist said he believes they are good. :D xx

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Post by Hurghada Lady » Sat Feb 28, 2009 10:51 pm

They sound good, you will have to report back weekly to let us all know how they are with you ;)

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Post by FABlux » Sun Mar 01, 2009 8:01 am

Good luck really hope they work, let us know please.

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Post by Goddess » Sun Mar 01, 2009 12:40 pm

Hooray!!! Lets hope they do the job and you get some well earned sleep.
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Post by Karenh » Sun Mar 01, 2009 8:27 pm

Ill keep my fingers crossed for you
A day without laughter is a day wasted! :lol: ;)

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Post by P666ats » Sat Mar 07, 2009 6:11 pm

Well ladies week one of taking the tablets is up so thought i would give you an up date. Still having the hot flushes but not as bad, sleeping better though (thank god). It says on the pack to take with other hrt but since there is none available i am going solo. Start week 2 tomorrow so fingers crossed i will start seeing more of a change. I'm off to Thailand on friday so if these buggers dont work i will be checking out there pharmacies. x

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Post by FABlux » Sun Mar 08, 2009 2:55 pm

Glad its helping a bit but the Thai pharmacies sound like a good idea ;)

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Post by P666ats » Sat Apr 11, 2009 10:12 am

Well ladies i'm back from Thailand and feeling good. The pharmacies over there are pretty good but decided to stay with the Klimadynon and i must say the hot flushes are very few and far between and i am sleeping like a log. The reason i didnt get any hrt from thailand was i didnt want to get dependant on something i may not be able to replace over here. So ladies if your in need of any i suggest the pharmacy by Abu Ashra on the Espalade.

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Post by FABlux » Sat Apr 11, 2009 3:51 pm

Welcome back, glad the tabs are working so well.

Will see what my GP says in June when I go back, hopefully he'll leave me on HRT & I will get a 12 month supply ;) Otherwise I will be scouring this thread again :roll: